Onco Bcg Injection

Product Description

Onco BCG Injection contains Bacillus Calmette-Guerin (BCG), a weakened form of the Mycobacterium bovis bacteria. It is primarily used in the treatment of bladder cancer and sometimes for urinary tract infections (UTIs) caused by bladder infections. It is an intravesical (into the bladder) treatment that stimulates the immune system to attack cancer cells in the bladder.

Key Uses:

1. Bladder Cancer Treatment: Onco BCG is mainly used for non-muscle invasive bladder cancer (NMIBC), specifically for superficial transitional cell carcinoma of the bladder. It helps reduce the risk of cancer recurrence after surgery.

2. Bladder Cancer Prevention: It is often used after transurethral resection of bladder tumors (TURBT) to prevent the recurrence of bladder cancer.

Mechanism of Action:

BCG works by stimulating the body™s immune system. When Onco BCG is introduced into the bladder, it triggers a local immune response that activates T-cells and other immune cells to attack the cancer cells. The immune cells recognize the cancer cells as foreign and help destroy them, which can prevent the cancer from coming back.

Common Side Effects:

• Urinary symptoms: These can include burning sensation or painful urination, frequent urination, or blood in the urine (hematuria).
• Fatigue or general weakness.
• Low-grade fever: This can occur after the treatment.
• Bladder irritation or discomfort.
• Muscle aches and joint pain.

Serious Side Effects:

• Systemic infections: In rare cases, BCG treatment can cause serious infections if the bacteria spread beyond the bladder.
• Severe allergic reactions: Symptoms can include rash, swelling, or difficulty breathing, and require immediate medical attention.
• Severe urinary tract infection: This is rare, but infection symptoms like fever, chills, or pain may require medical attention.

Dosage:

Onco BCG Injection is typically administered through the bladder (intravesical) once a week for a series of 6 weeks, followed by maintenance treatments. The exact dosage and schedule depend on the patient's condition and treatment plan. The injection is performed by a healthcare provider using a catheter to deliver the medication directly into the bladder.

Precautions:

• Infection risk: The patient should be monitored for signs of infection, and any systemic symptoms (such as fever) should be reported immediately.
• Urinary tract irritation: The medication can cause temporary irritation of the bladder lining, and measures may be taken to alleviate symptoms.
• Pregnancy and breastfeeding: Onco BCG should be avoided during pregnancy and breastfeeding due to the risk of transmission of the bacteria to the fetus or infant.

Summary:

Onco BCG Injection is a bladder cancer treatment that uses a weakened form of Mycobacterium bovis to stimulate the immune system to target and destroy cancer cells in the bladder. It is effective in preventing recurrence of non-muscle invasive bladder cancer after surgery. While generally well-tolerated, it can cause urinary discomfort, fatigue, and rare infections. Regular monitoring is necessary during treatment, and patients should be aware of possible signs of infection or severe reactions.