Enzalutamide Capsules 40 Mg (ENZALU)

Product Description

Enzalutamide Capsules 40 mg (ENZALU) contain enzalutamide, which is an androgen receptor inhibitor used primarily in the treatment of prostate cancer. It works by blocking the action of male hormones (androgens) like testosterone, which can fuel the growth of prostate cancer cells.

Common uses of Enzalutamide (ENZALU):

1. Metastatic castration-resistant prostate cancer (mCRPC): Enzalutamide is commonly used to treat prostate cancer that no longer responds to standard hormonal treatments (like castration) and has spread to other parts of the body.
2. Non-metastatic castration-resistant prostate cancer (nmCRPC): It is also used in patients with prostate cancer that is not yet metastatic but is resistant to standard hormonal treatments.
3. Adjuvant treatment: In some cases, it may be used in combination with other therapies to help reduce the risk of recurrence after surgery or radiation.

How it works:

Enzalutamide inhibits the androgen receptor, preventing androgens like testosterone from binding to the receptor on prostate cancer cells. This reduces the growth and spread of cancer by blocking the signaling pathway that typically promotes cancer cell proliferation.

Common side effects of Enzalutamide:

• Fatigue or tiredness
• Hot flashes
• Decreased libido (reduced sexual desire)
• Gynecomastia (breast tissue enlargement in men)
• Bone pain or joint pain
• Headache
• Nausea and diarrhea
• Seizures (though rare, this is a serious side effect)
• High blood pressure (hypertension)
• Fall risk or dizziness

Important considerations:

• Seizure risk: Enzalutamide can increase the risk of seizures, particularly in patients with a history of seizures or certain brain conditions. This risk should be closely monitored during treatment.
• Hormonal effects: Since it affects androgen receptors, enzalutamide can lead to hormonal changes, including decreased sexual function and changes in mood.
• Liver function: Liver enzymes should be monitored during treatment, as enzalutamide can impact liver function.
• Drug interactions: Enzalutamide can interact with other medications, especially those that affect liver enzymes (CYP3A4 inhibitors or inducers), so it's important to inform your healthcare provider about all medications you're taking.
• Pregnancy and breastfeeding: Enzalutamide is not recommended for use in women, especially during pregnancy, as it can harm a developing fetus. It should not be used while breastfeeding.

Administration:

Enzalutamide is typically taken as a capsule once a day, with or without food. Itïs important to take the medication exactly as prescribed and not to miss doses. If you miss a dose, follow the instructions your doctor has given you, but donït take two doses at once to make up for the missed one.

Enzalutamide can be an important part of prostate cancer treatment, especially for metastatic and castration-resistant forms, but like all cancer therapies, it requires careful monitoring for potential side effects.