Diclofenac Gel BP 1% w/w

Product Description

Diclofenac Gel BP 1% w/w is a topical anti-inflammatory medication used to relieve pain and inflammation associated with musculoskeletal conditions, such as arthritis, sprains, and strains. It contains Diclofenac Sodium as the active ingredient, which belongs to a class of drugs known as Nonsteroidal Anti-Inflammatory Drugs (NSAIDs).

Key Information about Diclofenac Gel BP 1% w/w:

Active Ingredient:

• Diclofenac Sodium 1% is the active component. Diclofenac works by inhibiting cyclooxygenase (COX) enzymes, which are involved in the production of prostaglandins. Prostaglandins are chemicals that promote inflammation, pain, and fever. By blocking their production, diclofenac helps reduce pain and inflammation.

Indications (Uses):

Diclofenac Gel 1% w/w is commonly used for:

• Relief of pain and inflammation from conditions like osteoarthritis or rheumatoid arthritis, particularly in joints such as the knees, elbows, or wrists.
• Soft tissue injuries, including sprains, strains, and bruises.
• Acute musculoskeletal injuries: To alleviate pain from sports injuries or other types of trauma.

Dosage:

• Diclofenac Gel 1% should be applied to the affected area of skin. The usual recommended amount is about 2-4 grams for each application, depending on the size of the affected area. Typically, it is applied 2 to 4 times daily.
• Avoid application on broken or irritated skin.
• Wash hands after applying the gel unless treating the hands.

Side Effects:

Common side effects may include:

• Skin irritation: Redness, itching, or a rash at the site of application.
• Dry or peeling skin at the application site.
• Burning or stinging sensation when applied.

Serious side effects are rare but may include:

• Severe allergic reactions, such as swelling or difficulty breathing.
• Photosensitivity: Increased sensitivity to sunlight, leading to sunburn or skin irritation.
• Ulcers or gastrointestinal bleeding: Although less common with topical use, NSAIDs like diclofenac can still cause these issues when absorbed through the skin.

Precautions:

• Avoid using on broken or damaged skin: This could increase absorption and the risk of side effects.
• Avoid contact with eyes and mucous membranes.
• Do not wrap or bandage the area tightly after applying the gel.
• Use cautiously in patients with a history of gastrointestinal issues, such as ulcers or bleeding problems, as systemic absorption can still occur.
• Pregnancy and breastfeeding: Should be used with caution during pregnancy, especially in the third trimester. Consult a doctor before use if breastfeeding.

Storage:

• Store at room temperature (between 15C to 25C).
• Keep the container tightly closed and out of direct sunlight.
• Keep out of reach of children.

Conclusion:

Diclofenac Gel BP 1% w/w is an effective topical treatment for relieving pain and inflammation associated with musculoskeletal conditions. It provides targeted relief without the systemic side effects typically seen with oral NSAIDs.